For pocket holes, I've seen people assemble inner/outer skins while wall is laying flat on the table so they can epoxy it, but then one ends up needing to run pocket holes thru both the inner and skeleton.
Absolutely, install the inner and outer skins while flat. You can dump a little weight by going to 1/8" Baltic on the interior.
Make sure you glass the exterior, or it will probably check under the Monstaliner and cause all kinds of grief. Putting down a layer of 4 or 6-ounce glass, while flat, is a simple thing.
There's no reason to run pocket screws to the outside. Do it from the inside. And set those holes while the wall is flat. The mattress will cover the holes, but they make pocket hole plugs you can add once the wall is attached to the floor to give it a cleaner look.
I also run a line of vertical screws through the exterior skin, into the floor, and set just below the surface. Once the wall is mounted, I mix a bit of thickened epoxy and cover the screw head.
Also, you don't need 9mm ply for the floor system. 1/4" (or 6mm) is fine as long as you have supporting joists. I used doubled 3/4" plywood for this, set on edge. They are very stiff.
Weight adds up quickly during a build.
Tony