All of the answers I've seen so far work fine.
Typically I run a bolt thru the floor, with a nut underneath. Yes, you might want to consider a counter bore for the bolt head.
But you could use self tapping screws if you have enough of them...
You want to consider the shear strength of the bolts or screws when sizing them. Especially if you have to stop quick... (or if you get stopped quick). Can you imagine backing into a campsite, hitting a tree, and your teardrop body comes off the trailer cause your screws were too small?
Mike...
The quality is remembered long after the price is forgotten, so build your teardrop with the best materials...