I'm going to caulk around the holes/tubing in my floor where the water lines pass through, I've already sealed the edges of the plywood. Caulk choices are:
Dap Alex Plus Acylic Latex plus Silicone, indoor/outdoor.
Lexel, petroleum based, indoor/outdoor.
Dap Butyl gutter and flashing (don't laugh, this stuff is great).
or.....??
I've learned here to avoid silicone around windows (used butyl for that).