I guess I should keep up with my own threads...
I've gone back and forth over the framing issue since I posted this. I was thinking along the lines of framed walls with paneling on the inside and aluminum on the outside. I've since changed my mind (fancy that) about the wall construction, and as it sits right now, I'm leaning more toward sandwich construction.
That'll most likely mean 1/4" ply outside skin, 3/4" white wood (fir, hemlock, etc...) framing, and either 1/8" or 1/4" ply inner skin.
As to redwood taking glue and fasteners, I've made several picnic tables and other outdoor furniture from redwood and have never had a problem with it taking glue or fasteners. I do understand that there's a big difference between framing and furniture, and that was the reason for my original question.
Thanks for all the feedback, folks! I really do appreciate every comment!