how should I seal this?

I will screw through the wall into the floor through aluminum trim. What is the best way to seal out the elements in terms of chemical or material. Is it adheasive caulking or rubber weather stripping or something else. Please edgeamacate me.
http://tnttt.com/album_ ... c_id=41761

http://tnttt.com/album_ ... c_id=41761