1/2 inch would be overkill. It would be better to spread out more fasteners than to just go with a few large ones.
I will be using sixteen (16) 3/8 inch bolts; 4 each along each of the front, rear, and two intermediate xmbrs. They will pass up through tabs ("clips") at the front and rear, and directly through the intermediate angle iron xmbrs; through blocking or 2x2 framing in the torsion box floor; into T-nuts recessed into the top surface of the floor frame, but hidden under the top floor skin. My trailer should not weigh more than 1500# loaded for bear. (We'll see.)
Here's a
chart showing the cross sectional area (tensile stress area) for coarse and fine thread bolts. The cross sectional area of a bolt at its threads is significantly smaller than the nominal size would suggest. A 1/4-20 bolt has a tensile area of 0.0318 in^2. Multiply this times your 6 bolts and you get 0.1908 in^2 total. Assume the bolt is low grade mild steel with a tensile strength of 36kips (a kip is 1000 #/in^2), multiple this by 2/3 for a factor of safety on yielding and the steel is good for 24kips. Times how much steel you have (24kips x 0.1908 in^2) and you get 4579 lbs. capacity. That's a static load capability applied gradually and assumed to be applied evenly over your whole trailer.
In reality, your trailer frame will be trying to flex putting greater strain on either the front and rear bolts together or the middle ones alone. Also there is shock loading to be considered, such as when hitting a pothole or bumping a curb. The braking forces of your car will cause the bolts to see a shear load as the cabin attempts to slide forward off of the trailer frame.
So for me and my 16 bolts, 3/8UNC and 1500# camper it goes like this...
0.0775 in^2 per bolt x 16 bolts x 24,000 #/in^2 all divided by 1500# = 19.8
10 is a good conservative dynamic load factor (your trailer would have to hit something pretty hard to develop 10g's), so I am almost double that. In my "book" (not really a book, just my TLAR) that is an equivalent safety factor of 2.
Purist engineers can most certainly show me where I have strayed from the science of static and kinematic design theory, and how my safety factor is not being calculated accurately due to conservatism, but I'm okay with that.

I know just enough about this stuff to be considered dangerous.
