Sandwich everything - talk me out of it.

I'm thinking about sandwich construction for everything - floor, walls, bulkheads, bed base (under bed storage likely), etc.; basically everything but cabinet doors (if I even use doors).
Walls would be 1/8" ply interior, 1" skeleton and extruded foam, 1/8" or 1/4" ply exterior.
Floor would probably be 1/2" ply base,1" skeleton and foam, and 1/8" or 1/4" top ply.
Everything else: 1/8" ply, 1/2" skeleton (likely poplar or pine) with 1/2" EPS or extruded foam for insulation and/or sound deadening, and 1/8" ply.
Of course, there would be blocks in the sandwiches for any attachment points.
Why shouldn't I?
As I plan my build and identify exact (or classes of) materials and components to use, I am constantly worrying about weight.
I want a light build. And I only have 2,200 lb Timbren suspension to work with.
"Hollowing out" the plywood used as bulkheads, cabinet faces, etc., seems like a reasonable opportunity to shave pounds. It's a lot of labor, I do recognize that. But I'm fighting a monster. Ounces are pounds and pounds are tons.
I'll do the math on actual weight savings for a cabinet bottom after I get home today. But even without the numbers, what are your thoughts...?
Walls would be 1/8" ply interior, 1" skeleton and extruded foam, 1/8" or 1/4" ply exterior.
Floor would probably be 1/2" ply base,1" skeleton and foam, and 1/8" or 1/4" top ply.
Everything else: 1/8" ply, 1/2" skeleton (likely poplar or pine) with 1/2" EPS or extruded foam for insulation and/or sound deadening, and 1/8" ply.
Of course, there would be blocks in the sandwiches for any attachment points.
Why shouldn't I?
As I plan my build and identify exact (or classes of) materials and components to use, I am constantly worrying about weight.
I want a light build. And I only have 2,200 lb Timbren suspension to work with.
"Hollowing out" the plywood used as bulkheads, cabinet faces, etc., seems like a reasonable opportunity to shave pounds. It's a lot of labor, I do recognize that. But I'm fighting a monster. Ounces are pounds and pounds are tons.
I'll do the math on actual weight savings for a cabinet bottom after I get home today. But even without the numbers, what are your thoughts...?