Skeletonizing: How much is too much?

My third motorcycle tent trailer build is beginning to take shape and I'd like to subtract some weight. I've read some of the threads here on skeletonizing plywood which I plan to try. I don't want to be greedy -- I'm hoping for a 25% to 33% weight reduction on the vertical panels. I don't plan to cut all the way through, but rather route out enough to leave 2 ply for the exterior skin. In this pic, the triangles on the exterior are for illustration, I will be removing inside material. I'm wondering...
Has there been any discussion in the forum on the *amount* of material that can be removed?
Are there preferred shapes for creating voids?
Are there any critical "do's" or "don'ts"?
Can this be done to a lesser extent on horizontal surfaces? I'm not taking anything out of the cargo box base where the half axles are mounted. However, the panel in the upper left is the cargo box top/upper bed panel. That panel seems like it might be a candidate. It will only bear about 100 lbs, on average (half body weight) and it will have support underneath
I am excited to try this technique. This is really going to help me cut a lot of weight. Appreciate any feedback, tips, thoughts.
Has there been any discussion in the forum on the *amount* of material that can be removed?
Are there preferred shapes for creating voids?
Are there any critical "do's" or "don'ts"?
Can this be done to a lesser extent on horizontal surfaces? I'm not taking anything out of the cargo box base where the half axles are mounted. However, the panel in the upper left is the cargo box top/upper bed panel. That panel seems like it might be a candidate. It will only bear about 100 lbs, on average (half body weight) and it will have support underneath
I am excited to try this technique. This is really going to help me cut a lot of weight. Appreciate any feedback, tips, thoughts.