Auntie M...sounds like you're already heading in a knowlegeable direction, but just to chime in...
My '01 2wd 4cyl 5spd Chevy S10 is my third S10 pickup. The Blazers are more or less the S10 and, depending on the year, the Blazer looks just like the S10 with an OEM designed bed.
My S10s have been more or less bullet-proof. They've all been 4cyl, 5spd, 2wd, lowest model end, no frills vehicles. I routinely get 25-28mpg on the highway, a bit less driving back and forth to work, and they do tend to drop a mile or two per gallon as they age. My first one was a '90, my second was a '95 club cab. I was driving a LOT more when I had those trucks, and traded each of them in with around 90-95K. The '01 just broke 60K because I stopped doing long-haul dog showing from 2001-2006, but in the last year I've put around 15K on it. It's been pretty well maintained, and I agree that's the key to these vehicles.
The only thing I've really had a problem with in my current S10 is the check engine light. Two years ago, I was broadsided by a kid who ran a red light. The damage to her Volvo was a lot worse than to my s10; I was worried the frame would be bent but it was fine. However, after the acident mysteriously the check engine light came on and wouldn't go off, and the A/C just stopped working. The accumulated skills of three mechanics finally figured out the engine light thing, but the A/C is still fruity. Sometimes it blows cool air, sometimes not so much. Since I don't have that much need for A/C here in CNY, I just roll down the windows and live with it when it's in a mood. The rest of the heating/defrosting/cooling system has been checked repeatedly and works just fine.
My 2nd s10 was a magnet for every avenging shopping cart it ever met, but that wasn't the truck's fault.

It was still a good truck.