We typically prefer Lowes. Primarly due to the Electrical section. and they are usually have more instock. The fact that stores are Cleaner than HD and we can actually find help is always a plus. Down side for us is the nearest Lowes is 60 miles away and HD is 5 min from work. The kicker is right behind the HD is a Proper Lumberyard. HD doesn't Try to compete with them from what I can see. two very different client bases.
Jim