I have done exactly this. I have a set of forward cabinets/shelves. When I did my design I specifically put in room to allow for ducting. So, in the front curved section I built in 2 ducts, an exhaust and an intake. These both exit underneath the trailer behind the first crossmember. I haven't installed the deflector/adapter yet, but the exterior part I'm making out of aluminum sheet. Primary vent faces backward and pulls/exhausts air from under the trailer. However, with the ideas the folks here came up with on adapting a window airconditioner to a diy petcool unit, the aluminum boxes also will have two 4" hose adapters in them. One for AC return air, one for AC supply air. Picked up a used 5000 btu unit for $15 and will build the adapter box for the unit out of aluminum sheet. This lets me mount the AC off the unit or under it. Hoses duct into the ductwork. Ducts have 2 5" fans in each section, exhaust and supply. I've been testing as building and here in Florida it has been steady in the mid 90s for a month now. Without air running and only the fans, the interior of the camper is 8-15 cooler than the outside temp in the shade. I also have foam insulation in walls/floor/roof.
It does work and I'm glad I did it.
Here is what I wrote on the posted photo...
Got the base cabinet/shelving/ductwork done today. Still need to wrap the ends with 1/8 ply, finish the doors. On the top the duct on the left is return and the one on the right is supply. Both exit through the floor, behind a crossmember. Both will end up having 12v fans in them. On the bottom part I'm fabricating a dual purpose vent mount, so I can either use it as straight ventilation or as an AC adapter, each duct is 5" x 8" opening on the bottom and 6x12 at the top. There will be another shelf on the right side, just above the powerstrip. Once the covers are all in you won't see any ductwork, wires, etc.

dave