I think know what Andrew is talking about, the driveshaft trying to flip the trailer if it is airborne.
It has nothing to do with the wheels or tires but the driveshaft connected to the trailer. It probably wouldn't flip the trailer because unless the driveshaft is coaxially mounted with the hitch, the hitch would probably bind up the driveshaft. If the driveshaft IS the hitch, then I'd wonder the same thing as Andrew.