The hole saw is what almost destroyed the side of the box. The plastic doesn't like high speed cutting. I have two more holes to cut. One long for the 120 volt power strip, and another round for the cigarette lighter socket. I'll do what I did for the panel. I first drew the hole pattern, then used an X-acto knife to cut initial grooves. I then used a reciprocating saw blade, I affixed to a handle, and cut the holes out manually. This way I get accurate smooth cuts. Takes several hours, and patience. Should have had more patience when cutting the holes for the wires.
I'll probably use the same method when I cut the two holes for the doggie A/C, the 1400 BTU A/C I just purchased. I don't know the diameter if the exhaust and intake holes. If they aren't too big, I can use the hole saw method. Also not sure how much this unit weighs. It is basically ah 8 inch cube in size. Regardless, I probably will have to add some kind of support between the trailer support studs, in order to mount it. I'll figure something out.
Also have that three inch diameter floor hole for for that A/C power cable pass. But I am not using the 30 amp cable off my generator. That is way too much. I'll just use the 20 amp socket to run the A/C, and whatever is needed during the day.
That work didn't seem hard, but it did send me to an early nap. Guess small trailer work is more difficult than working in a large one where you can stand up.

EDITED: Low, the holes are 1.5 inches diameter. I wanted to ensure I had more room than I needed to run the wires and the grounding cables, and in case ever need to install additional wiring. I doubt I need all four holes, but I tend to be cautious, and plan ahead for the just in case things. I can always cover any of the holes with a strip of plastic and weld it on with plastic/foam safe super glue. I'm going to try that Butyl tape I purchased. Just need to mold it around the hole.