I would think it's better to have a glued joint at each one & some type of mechanical fastener as well. I just use dowels for my side panels with one 3/8" pin at each joint. That's not really a lot of strength & it needs careful handling until the 1st skin is glued in place. Once this is done, the joints are locked by the glue & skin. When the 2nd skin is installed, it can't move at all. If you can't use fasteners (dowels, biscuits, pocket screws) at least use some glue & a clamp to hold things in place until the skin goes on.
If you look at the picture below, the block the panel is resting on is under the joint. Since my side panels are about 9' long, I had to join another foot of material onto the 3/4" side panel to get the full length I needed on a 4' x 8' sheet of plywood. Once it was trimmed into the frame, the only fastening was the three dowel pins & glue at each of the three joints. Not much wood there to hold, but the skin was enough to stabilize this joint & make it work. It's plenty strong enough once the skin is on.
