AirTabs are just a brand name of (expensive, but nicely made) vortex generator. You can make something similar from trapezoidal bits of aluminum sheet bent in a vice and some mounting tape - here's a nice
Australian car article about them. Note that microlight aircraft use bent-aluminum VGs and this is the shape that NASA has tested, so don't get hoodwinked by AirTab propaganda about their VG shape. VGs are cheap enough to be worth trying out - though fuel records of less than 1,000 miles are unlikely to be accurate enough to measure the change.
Vortex generators work by injecting energy into the boundary layer in the form of turbulence. So they always
use energy and the question is do they deliver enough aerodynamic benefit to pay back that energy? Towing a trailer is one place where they could deliver such a benefit by 'connecting' the tow vehicle and trailer together into one aerodynamic body. In practice I can't see a TTT achieving that, since the ideal would be for it to be really close to the tow vehicle, like with less than a foot gap. Some semi-trailer cabs and trailers are getting very close together and have the same cross section - then vortex generators look like they should be able to deliver real benefits.
But as a stick them anywhere to any vehicle tool - forget it.